Treating tobacco companies fairly but with no leap of faith

RESTORE--from deduction to leap of faith.

inhibition of pacemaker output in pacemaker-dependent patients and/or false triggering with tracking to the upper rate limit in patients with reduced left ventricular function may be detrimental. Therefore, we cannot support the approach of Martin and co-workers—that is, to leave the pacemaker sensing function activated. In contrast, we recommend deactivating the sensing function in pacemaker-d...

"Insufficient" but still "necessary"? EBPM's dangerous leap of faith: commentary on Porter and O'Halloran (2009).

In the opening lines of ‘The postmodernist war on evidence-based practice’ (Porter andO’Halloran, 2009), the authors erect a false binary between health care practice ‘informed by research’ and ‘those who argue that there should be no restrictions on the sources of knowledge used by practitioners’. This, the authors submit, is the distinction between the evidence-based approach and the postmode...

Drug-eluting coronary stents: faith and hope, but no charity.

Commentary All editorial matter in CMAJ represents the opinions of the authors and not necessarily those of the Canadian Medical Association. J udging from the large number of publications on the cost-effectiveness of drug-eluting coronary stents, there is an emerging international consensus that the price tag for the 2 commercially available drug-eluting stents is excessive (approximately $150...

A global health fund: a leap of faith?

Leptin and the obesity hypoventilation syndrome: a leap of faith?

he discovery of the anti-obesity hormone leptin (the name is derived from the Greek " leptos " meaning " thin "), the product of the ob gene, 1 has fuelled a recent surge of interest in the mechanisms regulating mammalian fat stores. Leptin, a 16 kD protein of 167 amino acids with a similar crystal structure to cytokines, 2 is produced primarily by white adipose tissue. 3 The hormone elicits ap...